烟基因突变：一生之痛，无法逆转
大家好，我是烟评网站的编辑顾衡。作为一名理科出身的测评编辑，我深知数据的力量。今天，我要和大家分享一个令人震惊的事实：烟不仅损害身体健康，更会在基因层面留下不可磨灭的痕迹。根据最新的研究，烟者体内的基因突变会伴随一生，即使戒烟也无法逆转。这让我深感烟的危害远超我们的想象，也提醒我们要更加珍惜健康，远离烟草。
双语：烟的基因突变会伴随你一生
中国烟网讯：烟有害身体健康已经人尽皆知，近些年已经有越来越多的人加入戒烟行列。大多数人都觉得，戒烟了总没事儿了吧？最新研究结果显示，真相并非如此：研究显示，烟的基因突变会伴随你一生。Smoking leaves an "archaeological record" of the hundreds of DNA mutations it causes, scientists have discovered.
科学家研究发现，烟会DNA突变，给人留下数百种基因突变的“永久记录”。
Having sequenced thousands of tumour genomes, they found a 20-a-day oker would rack up an average of 150 mutations in every lung cell each year.
在对数千个肿瘤基因组进行测序后，科学家发现每天烟20支的人每年每个肺细胞累积平均有150个基因突变。
The changes are permanent, and persist even if someone gives up oking.
这些突变是永久且的，即使烟者戒烟也不可逆。
Researchers say ysing tumour DNA may help explain the underlying causes of other cancers.
研究人员说，分析肿瘤DNA能帮助解释其他癌症的深层原因。
Pamela Pugh, , was diagnosed with lung cancer in 2013. She started oking aged 17 and quit in her early 50s.
岁的帕梅拉-皮尤2013年被诊断患有肺癌。她自17岁开始烟，近50岁时戒烟。
But she said: "Even though I gave up many years ago, the effects of oking caught up with me.
但她说：“尽管我很多年前就戒烟了，但烟的影响一直在。”
"Had I known as a ager that oking caused mutations which would stay with me for life then I would never had started".
“如果时我知道烟的基因突变一生都会跟随着我，那么我绝不会开始烟。”
The study, in the journal Science, was cared out by an international group, including the Wellcome Trust Sanger Institute in Cambdgeshire and the Los Alamos National Laboratory in New Mexico.
这项研究发表在《科学》期刊上，由一个国际研究组研究得出，包括英国剑桥郡的基金会桑格研究院，以及美国新墨西哥州的洛斯阿拉莫斯国家实验室。
The ysis shows a direct link between the number of cigarettes oked in a lifetime and the number of mutations in tumour DNA.
研究显示，人一生中烟的总数量和肿瘤DNA变异的数量之间存在直接关系。
The authors found that, on average, oking a packet of cigarettes a day led to:
研究作者发现，平均来讲，每天一包烟会：
150 mutations in each lung cell every year
每年每个肺部细胞中有150个基因突变。
97 in the larynx or voice box
喉部或喉头97个突变
23 in the mouth
口腔部位23个突变
18 in the bladder
18个突变
six in the liver
肝脏6个突变
Joint lead author Prof Sir Mike Stratton, from the Wellcome Trust Sanger Institute, said: "The more mutations there are, the higher the chance that these will occur in the key genes that we call cancer genes, which convert a normal cell into a cancer cell."
研究报告的合作主创者，来自基金会桑格研究院的迈克-斯特拉顿教授说：“突变越多，关键基因，也就是我们所说的癌症基因发生突变的几率也就越大，这会将正常细胞转变为癌细胞。”
There are 35,000 deaths a year in the UK from lung cancer, and it is estimated that nine out of 10 cases are preventable.
英国每年有3.5万人死于癌症，据估计其中九成可以预防。
烟的基因突变问题不容忽视，它警示着我们健康的重要。作为烟评网站的编辑，我希望通过我的文章，能够让大家更加了解烟的危害，从而远离烟草，拥抱健康的生活。感谢大家的阅读，我是顾衡，我们下期再见！
